Reymond Research Group

The Reymond Research Group would like to welcome its new group member: Leon Rebhan (Ph.D. Student).

Check out our latest paper Inverse Polyamidoamine (i-PAMAM) Dendrimer Antimicrobials in Helvetica Chimica Acta by Etienne Bonvin! We redesigned polyamidoamine dendrimers by moving the carbonyl across the amide nitrogen to form inverse PAMAMs. Our i-PAMAMs are pure by HPLC, stable, and show potent antibacterial effects. https://doi.org/10.1002/

Reymond Group Networking Symposium took place successfully on Friday, March 24th! We are happy to see everyone, including some of our former group members in this great group reunion!

Reymond Group Networking Symposium is taking place on Friday 24.03.2023 in Gemeinschaftshörsaal! Everyone is welcome, don´t miss out! Zoom link: https://unibe-ch.zoom.us/j/65933453540?pwd=bkdiNDFNNkp6NUMwUjduaGJWZDFjQT09

The paper Synthesis and characterisation of fluorescent substrates for eukaryotic protein N-glycosylation is now available online in Tetrahedron! Check it out: https://www.sciencedirect.com/science/article/pii/S0040402023001436 Keywords: Carbohydrates; Fluorescence; Dolichol; Chitobiose; Mannose; Protein glycosylation Abstract: Herein we report the synthesis of two fluorescently labelled analogues of C25

The Reymond Research Group would like to welcome its new group member: Matheus Andrade Meirelles (Post-Doctoral Researcher).

A warm welcome to the Reymond group to Maedeh Darsaraee! Maedeh is starting a PhD in the exciting field of Machine Learning and Chemoinformatics.

The Reymond Research Group would like to welcome its new group member: Yves Grandjean (Ph.D. Student).

The paper Dipropylamine for 9-Fluorenylmethyloxycarbonyl (Fmoc) Deprotection with Reduced Aspartimide Formation in Solid-Phase Peptide Synthesis is now published in ACS Omega! Check it out: Dipropylamine for 9-Fluorenylmethyloxycarbonyl (Fmoc) Deprotection with Reduced Aspartimide Formation in Solid-Phase Peptide Synthesis Abstract: Herein, we report dipropylamine (DPA) as a fluorenylmethyloxycarbonyl (Fmoc) deprotection reagent to

Our paper Molecular Framework Analysis of the Generated Database GDB-13s (Ye Buehler and Jean-Louis Reymond, J. Chem. Inf. Model., 2023, 63, 2, 484-492, doi.org/10.1021/acs.jcim.2c01107) has been chosen to be featured on the cover of the January issue of Journal of Chemical Information and Modeling.

Our paper Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase is published in Nature Chemical Biology! Abstract: C-linked glycosylation is essential for the trafficking, folding and function of secretory and transmembrane proteins involved in cellular communication processes. The tryptophan C-mannosyltransferase (CMT) enzymes that install the modification attach a mannose to

We currently have an open PhD position in our group! Details can be found here.

The Reymond group wishes you a Merry Christmas and a Happy New Year 2023! Illustration: Artistic AI image generated by Midjourney, using a figure from our published paper: Molecular Framework Analysis of the Generated Database GDB-13s, Ye Buehler and Jean-Louis Reymond, J. Chem. Inf. Model., 2022 https://pubs.acs.org/

Three projects within the interdisciplinary network National Center of Competence in Research (NCCR) TransCure contributed by our group are now published in CHIMIA, archived in Vol. 76 No. 12 (2022): NCCR TransCure - Excellence in Membrane Transport Research 2010-2022! NCCR TransCure, funded by the Swiss National Science Foundation and the

The paper on Bemis and Murcko molecular frameworks of GDB-13s molecules is now published in JCIM! Here we assessed the originality of GDB and found out that many exclusive molecular frameworks in GDB might be the most relevant targets for synthetic chemistry aiming at innovative molecules. Check it out: Molecular