Reymond Research Group

University of Bern

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Open PhD position!

Ye Buehler

Jan 9, 2023

We currently have an open PhD position in our group!
Details can be found here.

A View on Molecular Complexity from the GDB Chemical Space

Check out our latest publication A View on Molecular Complexity from the GDB Chemical Space in JCIM! Abstract One recurring question when choosing which molecules to selectfor investigation is that of molecular complexity: is there a price to pay forcomplexity in terms of synthesis difficulty, and does complexity have anything

May 16, 2025 1 min read

Exploring Simple Drug Scaffolds from the Generated Database Chemical Space Reveals a Chiral Bicyclic Azepane with Potent Neuropharmacology

Check out our latest publication Exploring Simple Drug Scaffolds from the Generated Database Chemical Space Reveals a Chiral Bicyclic Azepane with Potent Neuropharmacology in Journal of Medicinal Chemistry! Abstract To assess how much structural diversity remains unexploited in simple drug scaffolds, we investigated ring systems functionalized with amine handles. Starting

Apr 25, 2025 1 min read

Antimicrobial Peptide-Peptoid Macrocycles from the Polymyxin B2 Chemical Space

Check out our latest publication Antimicrobial Peptide-Peptoid Macrocycles from the Polymyxin B2 Chemical Space in Journal of the Gesellschaft Deutscher Chemiker, Angewandte Chemie International Edition! Abstract Macrocycles have emerged as important new modalities in drug discovery. In the context of addressing the global threat of antimicrobial resistance, here we used

Apr 4, 2025 1 min read

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