Reymond Research Group

University of Bern

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Open PhD position!

Ye Buehler

Jan 9, 2023

We currently have an open PhD position in our group!
Details can be found here.

Peptide Dendrimers Transfecting CRISPR/Cas9 Plasmid DNA: Optimization and Mechanism

Check out our latest paper Peptide Dendrimers Transfecting CRISPR/Cas9 Plasmid DNA: Optimization and Mechanism in RSC Chemical Biology! We optimize a peptide dendrimer transfection reagent to deliver a large CRISPR/Cas9 plasmid DNA into cells, elucidate its delivery mechanism, and demonstrate its gene editing efficiency. Abstract Gene editing by

Aug 4, 2024 1 min read

One Chiral Fingerprint to Find Them All

Check out our latest paper One Chiral Fingerprint to Find Them All in Journal of Cheminformatics! Abstract Molecular fingerprints are indispensable tools in cheminformatics. However, stereochemistry is generally not considered, which is problematic for large molecules which are almost all chiral. Herein we report MAP4C, a chiral version of our

May 14, 2024 1 min read

Can Large Language Models Predict Antimicrobial Peptide Activity and Toxicity?

Check out our latest paper Can Large Language Models Predict Antimicrobial Peptide Activity and Toxicity? in RSC Medicinal Chemistry! Abstract Antimicrobial peptides (AMPs) are naturally occurring or designed peptides up to a few tens of amino acids which may help address the antimicrobial resistance crisis. However, their clinical development is

May 2, 2024 1 min read

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