Congratulations to our former group member Dr. Philippe Schwaller, who currently works as postdoctoral researcher at IBM Research Europe, to his appointment to the EPFL as Tenure Track Assistant Professor of Chemistry at the School of Basic Sciences! https://www.ethrat.ch/
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Read our review article on peptide dendrimers that's published in Chimia: "Peptide Dendrimers: From Enzyme Models to Antimicrobials and Transfection Reagents". Aiming at studying cooperativity effects between amino acids in easily accessible protein models, we have explored the chemistry of peptide dendrimers,
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The research article "Machine Learning Designs Non-Hemolytic Antimicrobial Peptides" just got published in Chemical Science! Antimicrobial peptides (AMPs) offer a unique opportunity to address antibiotic resistance, which is one of the major global public health threats. Most AMPs are membrane disruptive amphiphiles,
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The research article "Predicting Enzymatic Reactions with a Molecular Transformer" just got published in Chemical Science! The use of enzymes for organic synthesis allows for simplified, more economical and selective synthetic routes not accessible to conventional reagents. However, predicting whether a particular
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The research article "Prediction of chemical reaction yields using deep learning" was recently published in Machine Learning: Science and Technology. Artificial intelligence is driving one of the most important revolutions in organic chemistry. Multiple platforms, including tools for reaction prediction and synthesis
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The research article "The antibacterial activity of peptide dendrimers and polymyxin B increases sharply above pH 7.4" was recently published in Chemical Communications. pH-activity profiling reveals that antimicrobial peptide dendrimers (AMPDs) kill Klebsiella pneumoniae and Methicillin-resistant Staphylococcus aureus (MRSA) at pH
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Our research article regarding discovery of a novel and selective Janus Kinase inhibitor was selected by the editorial board of SYNFACTS for its important insights into chemical synthesis! The full article can be found here. Congratulations to all contributors!
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The research article "Extraction of organic chemistry grammar from unsupervised learning of chemical reactions" was recently published in Nature Advances. Humans use different domain languages to represent, explore, and communicate scientific concepts. During the last few hundred years, chemists compiled the language
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The Review article "Peptides in chemical space" was recently published in Medicine in Drug Discovery. The chemical space of peptides represents an extremely large reservoir of potentially bioactive compounds. Recent advances in computer hardware and software have led to a wide application
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