Ye Bühler-Feng

Improved fluorescence assays to measure the defects associated with F508del-CFTR allow identification of new active compounds
Publications

Improved fluorescence assays to measure the defects associated with F508del-CFTR allow identification of new active compounds

The paper Improved fluorescence assays to measure the defects associated with F508del-CFTR allow identification of new active compounds has been published by the British Journal of Pharmacology. Cystic fibrosis (CF) is a debilitating disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which codes for a
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Fluorescent Agonists of the α7 Nicotinic Acetylcholine Receptor Derived from 3-Amino-Quinuclidine
Publications

Fluorescent Agonists of the α7 Nicotinic Acetylcholine Receptor Derived from 3-Amino-Quinuclidine

The paper Fluorescent Agonists of the α7 Nicotinic Acetylcholine Receptor Derived from 3-Amino-Quinuclidine has been accepted for publication by Helvetica Chemica Acta. Here we asked the question whether fluorescence labelled small molecule agonists of the α7 nicotinic acetylcholine receptor (nAChR) might be identified to enhance receptor studies. Enantiomerically pure 3-amino-quinuclidines
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