Reymond Research Group

The paper Fluorescent Agonists of the α7 Nicotinic Acetylcholine Receptor Derived from 3-Amino-Quinuclidine has been accepted for publication by Helvetica Chemica Acta. Here we asked the question whether fluorescence labelled small molecule agonists of the α7 nicotinic acetylcholine receptor (nAChR) might be identified to enhance receptor studies. Enantiomerically pure 3-amino-quinuclidines

The paper Discovery of a Selective Aurora A Kinase Inhibitor by Virtual Screening has been accepted for publication in the Journal of Medicinal Chemistry. Here we report the discovery of a selective inhibitor of Aurora A, a key regulator of cell division and potential anti-cancer target. We used atom category