Reymond Research Group


University of Bern


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BIGCHEM: Challenges and Opportunities for Big Data Analysis in Chemistry

The paper "BIGCHEM: Challenges and Opportunities for Big Data Analysis in Chemistry" has been accepted for publication by Molecular Informatics. http://onlinelibrary.wiley.com/doi/10.1002/minf.201600073/full The increasing volume of biomedical data in chemistry and life sciences requires the development of new methods and approaches for their handling. Here, we briefly discuss some challenges and opportunities of this »

Fluorescent Agonists of the α7 Nicotinic Acetylcholine Receptor Derived from 3-Amino-Quinuclidine

The paper "Fluorescent Agonists of the α7 Nicotinic Acetylcholine Receptor Derived from 3-Amino-Quinuclidine" has been accepted for publication by Helvetica Chemica Acta. http://onlinelibrary.wiley.com/doi/10.1002/hlca.201600120/full Here we asked the question whether fluorescence labelled small molecule agonists of the α7 nicotinic acetylcholine receptor (nAChR) might be identified to enhance receptor studies. Enantiomerically pure 3-amino-quinuclidines appended with »

Discovery of a Selective Aurora A Kinase Inhibitor by Virtual Screening

Tags: publications

The paper "Discovery of a Selective Aurora A Kinase Inhibitor by Virtual Screening" has been accepted for publication in the Journal of Medicinal Chemistry. http://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.6b00709 Here we report the discovery of a selective inhibitor of Aurora A, a key regulator of cell division and potential anti-cancer target. We used atom category extended »

Welcome to the New GDB Website

Tags: Administrative

Welcome to the new website of the Reymond group. The content of the "Home" page and the "Cheminformatics" page has been moved to the "Tools" and "Downloads" pages. You will find the mapplet software available for download here, while the GDB databases can be found here. »