Reymond Research Group

University of Bern


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Medicinal Chemistry Aware Database GDBMedChem

Tags: Publications

The paper Medicinal Chemistry Aware Database GDBMedChem has been published by Molecular Informatics. The generated database GDB17 enumerates 166.4 billion possible molecules up to 17 atoms of C, N, O, S and halogens following simple chemical stability and synthetic feasibility rules,
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PubChem and ChEMBL beyond Lipinski

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The paper PubChem and ChEMBL beyond Lipinski has been published by Molecular Informatics. Seven million of the currently 94 million entries in the PubChem database break at least one of the four Lipinski constraints for oral bioavailability, 183,185 of which are
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Antimicrobial Peptide Dendrimer Chimera

Tags: Publications

The paper Antimicrobial Peptide Dendrimer Chimera has been accepted by Helvetica Chimica Acta. Abstract We recently reported the discovery of an antimicrobial peptide dendrimers (AMPDs) acting by a membrane disruptive mechanism against multidrug resistant pathogenic bacteria. Here we combined amino acid sequence
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